Nootropic & Cognitive Peptides

Peptides that enhance cognitive function, including focus, memory, neuroprotection, and neuroplasticity. These range from Russian-approved peptides like Semax and Selank to research compounds like Dihexa.

All Nootropic & Cognitive Peptides (4)

Semax

Compoundable (Rx)

Nootropic Peptides

Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone, fragment 4-10) developed by the Russian Institute of Molecular Genetics. ...

Cognitive enhancementNeuroprotectionFocus & attention

Selank

Compoundable (Rx)

Nootropic Peptides

Selank is a synthetic analog of the naturally occurring immunomodulatory peptide tuftsin, developed at the Russian Institute of Molecular Genetics alo...

Anxiety reductionCognitive enhancementImmune modulation

Dihexa

Research Only

Nootropic Peptides

Dihexa is an oligopeptide derived from angiotensin IV that has demonstrated extraordinary cognitive enhancement properties in animal studies — reporte...

Cognitive enhancementMemory improvementNeuroprotection

DSIP

Compoundable (Rx)

Nootropic Peptides

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring neuropeptide that promotes delta wave (deep) sleep. It was first isolated from rabbit bra...

Sleep quality improvementStress reductionPain modulation

Comparison Table

Peptide	Legal Status (USA)	Evidence	Administration	Half-Life	Primary Uses
Semax	Compoundable (Rx)	BModerate Evidence	nasal, subcutaneous	~3-5 minutes (rapid onset, sustained effects)	Cognitive enhancementNeuroprotection+3
Selank	Compoundable (Rx)	BModerate Evidence	nasal, subcutaneous	~5-10 minutes (rapid onset, sustained effects)	Anxiety reductionCognitive enhancement+2
Dihexa	Research Only	CPreliminary Evidence	oral, subcutaneous, nasal	~4-6 hours	Cognitive enhancementMemory improvement+2
DSIP	Compoundable (Rx)	CPreliminary Evidence	subcutaneous, nasal, intravenous	~15-25 minutes (but effects last hours)	Sleep quality improvementStress reduction+2