Best Peptides for Cognitive Enhancement

Peptides that improve focus, memory, neuroplasticity, and protect against cognitive decline through BDNF elevation and neurotransmitter modulation.

Recommended Peptides (4)

Semax

Compoundable (Rx)

Nootropic Peptides

Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone, fragment 4-10) developed by the Russian Institute of Molecular Genetics. ...

Cognitive enhancementNeuroprotectionFocus & attention

Selank

Compoundable (Rx)

Nootropic Peptides

Selank is a synthetic analog of the naturally occurring immunomodulatory peptide tuftsin, developed at the Russian Institute of Molecular Genetics alo...

Anxiety reductionCognitive enhancementImmune modulation

Dihexa

Research Only

Nootropic Peptides

Dihexa is an oligopeptide derived from angiotensin IV that has demonstrated extraordinary cognitive enhancement properties in animal studies — reporte...

Cognitive enhancementMemory improvementNeuroprotection

DSIP

Compoundable (Rx)

Nootropic Peptides

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring neuropeptide that promotes delta wave (deep) sleep. It was first isolated from rabbit bra...

Sleep quality improvementStress reductionPain modulation

Quick Comparison

Peptide	Class	Legal Status (USA)	Evidence	Administration	Dosage
Semax	Nootropic Peptides	Compoundable (Rx)	BModerate Evidence	nasal, subcutaneous	200-600mcg nasal, 1-2x daily
Selank	Nootropic Peptides	Compoundable (Rx)	BModerate Evidence	nasal, subcutaneous	250-500mcg nasal, 1-3x daily
Dihexa	Nootropic Peptides	Research Only	CPreliminary Evidence	oral, subcutaneous, nasal	5-20mg oral; 1-5mg subcutaneous
DSIP	Nootropic Peptides	Compoundable (Rx)	CPreliminary Evidence	subcutaneous, nasal, intravenous	100-300mcg before bed