Best Peptides for Anti-Aging & Longevity

Peptides that target core mechanisms of biological aging including telomere maintenance, senescent cell clearance, mitochondrial function, and growth hormone decline.

Recommended Peptides (6)

Epitalon

Compoundable (Rx)

Anti-Aging Peptides

Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on epithalamin, a peptide produced by the pineal gland. It is one of the most studied ant...

Anti-agingTelomere maintenanceSleep regulation

GHK-Cu

Compoundable (Rx)

Anti-Aging Peptides

GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine. It dec...

Anti-agingSkin rejuvenationWound healing

FOXO4-DRI

Research Only

Anti-Aging Peptides

FOXO4-DRI is a senolytic peptide that selectively induces apoptosis (programmed cell death) in senescent cells — damaged cells that accumulate with ag...

Senescent cell clearanceAnti-agingTissue rejuvenation

SS-31

In Clinical Trials

Mitochondrial Peptides

SS-31 (elamipretide) is a mitochondria-targeted peptide that concentrates 1000-fold in the inner mitochondrial membrane. It protects mitochondrial fun...

Mitochondrial protectionHeart failureAge-related decline

Humanin

Research Only

Mitochondrial Peptides

Humanin is a 24-amino acid mitochondria-derived peptide (MDP) that plays protective roles against Alzheimer's disease, cardiovascular disease, and age...

NeuroprotectionCardiovascular protectionAnti-aging

MOTS-c

Compoundable (Rx)

Metabolic Peptides

MOTS-c is a mitochondrial-derived peptide encoded within the 12S rRNA gene. It functions as an exercise mimetic, activating AMPK pathways similar to p...

Exercise mimeticMetabolic optimizationInsulin sensitivity

Quick Comparison

Peptide	Class	Legal Status (USA)	Evidence	Administration	Dosage
Epitalon	Anti-Aging Peptides	Compoundable (Rx)	CPreliminary Evidence	subcutaneous, intravenous	5-10mg daily for 10-20 day cycles
GHK-Cu	Anti-Aging Peptides	Compoundable (Rx)	BModerate Evidence	subcutaneous, topical	1-2mg daily (injectable); 1-2% concentration (topical)
FOXO4-DRI	Anti-Aging Peptides	Research Only	CPreliminary Evidence	subcutaneous, intravenous	5-50mg per session (variable protocols)
SS-31	Mitochondrial Peptides	In Clinical Trials	BModerate Evidence	subcutaneous, intravenous	4mg daily (clinical trials)
Humanin	Mitochondrial Peptides	Research Only	CPreliminary Evidence	subcutaneous	1-5mg daily (experimental)
MOTS-c	Metabolic Peptides	Compoundable (Rx)	CPreliminary Evidence	subcutaneous	5-10mg weekly